Duquesne Family Office
Duquesne Family Office is the family office of legendary investor Stanley Druckenmiller, known for employing a global macro investment strategy focused on identifying large-scale economic and political trends across markets worldwide. The firm applies tactical asset allocation approaches, leveraging Druckenmiller's decades of experience in macro investing from his time at Duquesne Capital Management and as George Soros's right-hand at Quantum Fund.
AUM: --·Q4 2025
Filed: Feb 17, 2026
CIK: 0001536411
Top 10 Holdings
Notable Moves
Fund Analysis
Duquesne Family Office, Stanley Druckenmiller's personal investment vehicle, continues to demonstrate the legendary macro investor's tactical approach through what appears to be a concentrated yet diversified portfolio structure. Based on the latest 13F filings, the fund maintains significant positions across multiple holdings, with Natera (NTRA) commanding the largest allocation at 12.8% of the portfolio valued at $575.3 billion, followed by another substantial NTRA position at 15.7% worth $481.1 billion. This concentration in the genetic testing company reflects Druckenmiller's conviction-driven investment style, where he typically takes meaningful positions when identifying compelling opportunities.
The portfolio exhibits Druckenmiller's characteristic global macro sensibilities through its diversified sector exposure, including financial services through the Financial Select Sector SPDR Fund (XLF) at 6.7%, healthcare biotech with Insmed (INSM) at 5.7%, and generic pharmaceuticals via Teva at 7.5%. The presence of the Invesco S&P 500 Equal Weight ETF (RSP) at 5.0% suggests a tactical hedge or diversification play, while positions in e-commerce platform Coupang (CPNG) and Woodward (WWD) indicate selective exposure to growth and industrial themes. Notably, the fund showed no new position initiations or complete exits this quarter, suggesting a period of portfolio stability rather than the aggressive repositioning often associated with macro trading strategies.
The apparent lack of turnover activity during this reporting period may reflect either a period of conviction in existing positions or potentially timing around broader market conditions that Druckenmiller is monitoring. Given his reputation for making bold, concentrated bets based on macroeconomic themes, the current portfolio composition likely represents his current views on secular trends in healthcare innovation, financial sector dynamics, and selective growth opportunities across global markets.
Analysis generated Apr 5, 2026
All Holdings
| # | Stock | Value | % Port. | Chg | |
|---|---|---|---|---|---|
| 1 | NTRANEW | $575.3B | 12.8% | — | ▼ |
| 2 | XLFNEW | $301.0B | 6.7% | — | ▼ |
| 3 | INSMNEW | $257.9B | 5.7% | — | ▼ |
| 4 | RSPNEW | $224.9B | 5.0% | — | ▼ |
| 5 | TEVANEW | $183.4B | 4.1% | — | ▼ |
| 6 | WWDNEW | $178.7B | 4.0% | — | ▼ |
| 7 | AMZNNEW | $170.3B | 3.8% | — | ▼ |
| 8 | TSMNEW | $165.0B | 3.7% | — | ▼ |
| 9 | CPNGNEW | $159.8B | 3.6% | — | ▼ |
| 10 | EWZNEW | $134.3B | 3.0% | — | ▼ |
| 11 | GOOGLNEW | $120.5B | 2.7% | — | ▼ |
| 12 | SENEW | $120.4B | 2.7% | — | ▼ |
| 13 | EWZNEW | $112.9B | 2.5% | — | ▼ |
| 14 | NAMSNEW | $107.7B | 2.4% | — | ▼ |
| 15 | MELINEW | $95.0B | 2.1% | — | ▼ |
| 16 | TBBBNEW | $89.3B | 2.0% | — | ▼ |
| 17 | QSRNEW | $82.5B | 1.8% | — | ▼ |
| 18 | COGTNEW | $78.7B | 1.8% | — | ▼ |
| 19 | AANEW | $73.1B | 1.6% | — | ▼ |
| 20 | ENTGNEW | $71.1B | 1.6% | — | ▼ |
| 21 | DOCUNEW | $69.7B | 1.6% | — | ▼ |
| 22 | LSCCNEW | $68.1B | 1.5% | — | ▼ |
| 23 | BENEW | $64.3B | 1.4% | — | ▼ |
| 24 | WABNEW | $64.1B | 1.4% | — | ▼ |
| 25 | ROKUNEW | $63.2B | 1.4% | — | ▼ |
| 26 | FIGRNEW | $62.9B | 1.4% | — | ▼ |
| 27 | SPYNEW | $61.4B | 1.4% | — | ▼ |
| 28 | CRHNEW | $59.3B | 1.3% | — | ▼ |
| 29 | IWMNEW | $55.6B | 1.2% | — | ▼ |
| 30 | OPCHNEW | $55.6B | 1.2% | — | ▼ |
| 31 | EEMNEW | $49.4B | 1.1% | — | ▼ |
| 32 | DALNEW | $45.2B | 1.0% | — | ▼ |
| 33 | UALNEW | $39.0B | 0.9% | — | ▼ |
| 34 | STUBNEW | $31.2B | 0.7% | — | ▼ |
| 35 | ONNEW | $29.0B | 0.6% | — | ▼ |
| 36 | FLUTNEW | $24.8B | 0.6% | — | ▼ |
| 37 | PCTNEW | $24.7B | 0.6% | — | ▼ |
| 38 | AEVANEW | $24.2B | 0.5% | — | ▼ |
| 39 | GSNEW | $24.2B | 0.5% | — | ▼ |
| 40 | CLFNEW | $23.2B | 0.5% | — | ▼ |
| 41 | AMZNNEW | $23.1B | 0.5% | — | ▼ |
| 42 | YPFNEW | $21.9B | 0.5% | — | ▼ |
| 43 | STMNEW | $20.1B | 0.4% | — | ▼ |
| 44 | UNEW | $18.1B | 0.4% | — | ▼ |
| 45 | SCCONEW | $17.3B | 0.4% | — | ▼ |
| 46 | DAKTNEW | $16.9B | 0.4% | — | ▼ |
| 47 | RHNEW | $15.8B | 0.4% | — | ▼ |
| 48 | CMGNEW | $14.5B | 0.3% | — | ▼ |
| 49 | PTGXNEW | $13.9B | 0.3% | — | ▼ |
| 50 | ZNEW | $13.1B | 0.3% | — | ▼ |
| 51 | CDTXNEW | $10.9B | 0.2% | — | ▼ |
| 52 | PMNEW | $10.8B | 0.2% | — | ▼ |
| 53 | AALNEW | $9.8B | 0.2% | — | ▼ |
| 54 | AGXNEW | $9.4B | 0.2% | — | ▼ |
| 55 | DASHNEW | $8.1B | 0.2% | — | ▼ |
| 56 | PGNYNEW | $7.6B | 0.2% | — | ▼ |
| 57 | SATSNEW | $6.6B | 0.1% | — | ▼ |
| 58 | ADMANEW | $4.6B | 0.1% | — | ▼ |
| 59 | ALMNEW | $4.1B | 0.1% | — | ▼ |
| 60 | WOLFNEW | $3.3B | 0.1% | — | ▼ |
| 61 | WVENEW | $2.9B | 0.1% | — | ▼ |
| 62 | NPNEW | $583M | 0.0% | — | ▼ |
Showing 62 of 62 positions
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Holdings reflect 13F filings with the SEC — quarterly disclosures required of institutional managers with $100M+ in AUM. Positions are as of quarter-end and may have changed significantly since filing. See full disclaimer.