§ 13F · FUND PROFILE
Siren, L.L.C..
Institutional filer · behavioral pattern: Other. Summary pending.
AUM · $1932.4T (13F)Positions · 111Turnover · — · Q4Filed · Feb 13, 2026
CONCENTRATION
—
Top 10 holdings
NEW BUYS
0
+$369.4T deployed
EXITS
0
No exits
SECTOR SHIFT
—
No prior quarter data
3YR HIT RATE
—
Top-5 overlap
§ 01 · TOP HOLDINGS
The book · Q4 2025
FILED FEB 13, 2026
| # | Ticker | Name | Shares | $ value | % port | Δ Q4 |
|---|---|---|---|---|---|---|
| 1 | SRRK | Scholar Rock Holding Corp | 10.83M | $476.8T | 14.2% | +17% |
| 2 | KYMR | Kymera Therapeutics Inc | 3.29M | $255.7T | 7.6% | −4% |
| 3 | ONC | BeOne Medicines AG | 500K | $151.9T | 4.5% | +1% |
| 4 | EWTX | Edgewise Therapeutics Inc | 4.53M | $112.4T | 3.4% | +16% |
| 5 | RVMD | Revolution Medicines Inc | 1.34M | $106.3T | 3.2% | +28% |
| 6 | CNTA | Centessa Pharmaceuticals PLC | 4.03M | $100.7T | 3.0% | +25% |
| 7 | ARWR | Arrowhead Pharmaceuticals Inc | 1.50M | $99.6T | 3.0% | −44% |
| 8 | BCAX | Bicara Therapeutics Inc | 5.22M | $87.8T | 2.6% | ±0% |
| 9 | OLMA | Olema Pharmaceuticals Inc | 3.30M | $82.5T | 2.5% | NEW |
| 10 | IRON | Disc Medicine Inc | 988K | $78.5T | 2.3% | +8% |
§ 02 · SECTOR ALLOCATION
Where the money is
Sector data pending
§ 03 · THE SIREN, SIGNAL
AC read
Siren, L.L.C. is a Other fund managing $1932436.0 trillion in assets. The fund runs a portfolio of 111 positions.
Read the full dossier →§ 04 · FILING HISTORY
Q-by-Q deltas
2 FILINGS
Q4 2025
Steady book
+0 buys · −0 exits · 0 changed
Q3 2025
Steady book
+0 buys · −0 exits · 0 changed
Q2 2025
Steady book
+0 buys · −0 exits · 0 changed
Q1 2025
Steady book
+0 buys · −0 exits · 0 changed