§ 13F · FUND PROFILE
SR One Capital Management, LP.
Institutional filer · behavioral pattern: Other. Summary pending.
AUM · $691.4T (13F)Positions · 12Turnover · — · Q4Filed · Feb 12, 2026
CONCENTRATION
—
Top 10 holdings
NEW BUYS
0
+$3.2T deployed
EXITS
0
No exits
SECTOR SHIFT
—
No prior quarter data
3YR HIT RATE
—
Top-5 overlap
§ 01 · TOP HOLDINGS
The book · Q4 2025
FILED FEB 12, 2026
| # | Ticker | Name | Shares | $ value | % port | Δ Q4 |
|---|---|---|---|---|---|---|
| 1 | ZBIO | Zenas BioPharma, Inc | 5.04M | $182.9T | 25.9% | +3% |
| 2 | ACLX | Arcellx, Inc. | 2.35M | $153.0T | 21.7% | ±0% |
| 3 | CRSP | CRISPR Therapeutics AG | 2.04M | $106.9T | 15.1% | ±0% |
| 4 | DSGN | Design Therapeutics, Inc. | 6.53M | $61.2T | 8.7% | ±0% |
| 5 | MLYS | Mineralys Therapeutics Inc. | 1.56M | $56.8T | 8.0% | −26% |
| 6 | SPRY | ARS Pharmaceuticals, Inc. | 4.01M | $46.8T | 6.6% | ±0% |
| 7 | ORIC | ORIC Pharmaceuticals, Inc. | 4.51M | $37.8T | 5.3% | ±0% |
| 8 | ALMS | Alumis Inc. | 1.96M | $19.1T | 2.7% | ±0% |
| 9 | ORKA | Oruka Therapeutics, Inc | 430K | $13.0T | 1.8% | ±0% |
| 10 | OCS | Oculis Holding AG | 641K | $12.8T | 1.8% | +99% |
§ 02 · SECTOR ALLOCATION
Where the money is
Sector data pending
§ 03 · THE SR SIGNAL
AC read
SR One Capital Management, LP is a Other fund managing $691412.2 trillion in assets. The fund runs a focused portfolio of just 12 positions.
Read the full dossier →§ 04 · FILING HISTORY
Q-by-Q deltas
1 FILINGS
Q4 2025
Steady book
+0 buys · −0 exits · 0 changed
Q3 2025
Steady book
+0 buys · −0 exits · 0 changed
Q1 2025
Steady book
+0 buys · −0 exits · 0 changed