← Back to Markets

KPTI

Karyopharm Therapeutics Inc · NASDAQ NMS - GLOBAL MARKET · Biotechnology

$7.21+$0.89 (+14.08%)

Prices delayed up to 5 minutes

AC Intelligence

AC Intelligence

AC Intelligence for KPTI is being prepared.

Key Stats

Key Stats

Open

$6.22

Day High

$7.25

Day Low

$5.96

Prev Close

$6.32

Volume

0

Avg Volume

2.8M

Day Change

+$0.89

Change %

+14.08%

Fundamentals

Fundamentals

P/B

22.52

EPS (TTM)

$-16.60

Market Cap

$116M

52-Wk Range

$3.51 — $10.99

Earnings History

Insider Activity

Who Owns This Stock

Who Owns KPTI

Other80.6%51 holders
Passive / Index8.7%3 holders
Systematic / Quant5.3%4 holders
Quality / Compounder2.4%2 holders
Dealer / Bank1.6%8 holders
Tactical / Macro1.3%2 holders

Based on Q4 2025 13F filings + AC behavioral model

70 institutional holders

Top Holders

1.Opaleye Management Inc.
$6844.8B
2.Affinity Asset Advisors, LLC
+464.5%$6547.3B
3.Ikarian Capital, LLC
$4007.9B
4.Vanguard Group
+812.9%$3320.1B
5.Soleus Capital Management, L.P.
$3238.4B
6.ADAGE CAPITAL PARTNERS GP, L.L.C.
$3100.9B
$2696.0B
$2361.8B
$2281.7B
10.BRAIDWELL LP
$2232.8B
11.Exome Asset Management LLC
$2175.2B
12.AMERIPRISE FINANCIAL INC
$2037.8B
13.Boxer Capital Management, LLC
$1858.7B
14.GROUP ONE TRADING LLC
+119.8%$1624.4B
15.BlackRock, Inc.
$1196.6B
16.TWO SIGMA INVESTMENTS, LP
$1095.1B
17.SUSQUEHANNA INTERNATIONAL GROUP, LLP
$1087.1B
18.Geode Capital Management
+90.4%$1080.8B
19.BOOTHBAY FUND MANAGEMENT, LLC
$1064.5B
20.Catalio Capital Management, LP
$1052.4B

Institutional Pressure

Market Regime:Strong Risk-Off (-0.62)
SELLINGBUYING
Mild Selling Pressure
Other(80.6%)
Passive / Index(8.7%)
Holds
Systematic / Quant(5.3%)
De-risking (mechanical)
Quality / Compounder(2.4%)
Holds through
Dealer / Bank(1.6%)
Facilitating
Tactical / Macro(1.3%)
Reducing rapidly

11% passive + quality floor won't sell.

Updated daily · Based on Q4 2025 filings + AC behavioral model

Sentiment Signals

Sentiment Signals

Insider ActivityNo insider transactions in last 90 daysSEC Form 4
↑↑Analyst Consensus11 buy, 2 hold, 0 sellFinnhub
↑↑Inst. Flows76 increased/new, 14 decreased/exited (13F)AC 13F Analysis

Sources: SEC Form 4, Finnhub, AC 13F Analysis

On AcidCapitalist

On AcidCapitalist

No recent mentions of KPTI on AcidCapitalist.

Data provided by Finnhub. Prices delayed up to 5 minutes.