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SPRO

Spero Therapeutics Inc · NASDAQ NMS - GLOBAL MARKET · Biotechnology

$2.67+$0.06 (+2.30%)

Prices delayed up to 5 minutes

AC Intelligence

AC Intelligence

AC Intelligence for SPRO is being prepared.

Key Stats

Key Stats

Open

$2.59

Day High

$2.69

Day Low

$2.48

Prev Close

$2.61

Volume

0

Avg Volume

363.7K

Day Change

+$0.06

Change %

+2.30%

Fundamentals

Fundamentals

P/E

17.3

P/B

2.22

EPS (TTM)

$0.05

Market Cap

$151M

52-Wk Range

$0.51 — $3.22

Earnings History

Insider Activity

Who Owns This Stock

Who Owns SPRO

Other74.9%35 holders
Passive / Index14.4%5 holders
Systematic / Quant7.1%4 holders
Tactical / Macro2.3%2 holders
Dealer / Bank1.1%10 holders

Based on Q4 2025 13F filings + AC behavioral model

57 institutional holders

Top Holders

1.GSK plc
$21414.1B
2.Pfizer Inc
0.0%$5504.3B
3.Vanguard Group
+589.0%$4179.8B
4.Renaissance Technologies
-11.9%$2981.3B
5.Alphabet Inc.
0.0%$2073.7B
6.Anson Funds Management LP
$1456.4B
7.Geode Capital Management
+387.8%$1015.6B
8.BlackRock, Inc.
$1007.5B
9.TWO SIGMA INVESTMENTS, LP
$868.1B
10.SUSQUEHANNA INTERNATIONAL GROUP, LLP
$684.3B
11.Vanguard Group
+1.4%$615.4B
12.Informed Momentum Co LLC
$508.1B
13.TWO SIGMA ADVISERS, LP
$504.7B
14.State Street
$489.7B
15.Citadel Advisors
+276.5%$480.7B
16.Ionic Capital Management LLC
-6.1%$456.5B
17.Citadel Advisors
+249.5%$446.3B
18.INTREPID FAMILY OFFICE LLC
+50.0%$384.4B
19.SEI INVESTMENTS CO
$307.6B
20.OMERS ADMINISTRATION Corp
$305.5B

Institutional Pressure

Market Regime:Strong Risk-Off (-0.62)
SELLINGBUYING
Mild Selling Pressure
Other(74.9%)
Passive / Index(14.4%)
Holds
Systematic / Quant(7.1%)
De-risking (mechanical)
Tactical / Macro(2.3%)
Reducing rapidly
Dealer / Bank(1.1%)
Facilitating
Quality / Compounder(0.1%)
Holds through

15% passive + quality floor won't sell.

Updated daily · Based on Q4 2025 filings + AC behavioral model

Sentiment Signals

Sentiment Signals

Insider ActivityNo insider transactions in last 90 daysSEC Form 4
Analyst Consensus0 buy, 3 hold, 3 sellFinnhub
↑↑Inst. Flows50 increased/new, 14 decreased/exited (13F)AC 13F Analysis

Sources: SEC Form 4, Finnhub, AC 13F Analysis

On AcidCapitalist

On AcidCapitalist

No recent mentions of SPRO on AcidCapitalist.

Data provided by Finnhub. Prices delayed up to 5 minutes.