§ BIOTECHNOLOGY
USD · BiotechnologyIONS
IONIS PHARMACEUTICALS INC
USDSector · BiotechnologyBeta · 0.41
§ 01 · PRICE
Price action
1D5D1M6MYTD1YMAX
OPEN 44.17HIGH 44.17LOW 43.2452W 23.95 — 86.74
§ 03 · SIGNAL STACK · WHAT THE INPUTS SAY
13F FLOW
286 increased/new, 161 decreased/exited (13F)
AC 13F Analysis
§ 04 · FUNDAMENTALS · THE BOOKS
| P/B | 26.20 | EPS (TTM) | -2.47 |
§ 05 · WHO OWNS IT
Top institutional holders
| Fund | Shares | % port | Δ Q/Q |
|---|---|---|---|
| Fidelity Management | 24.6M | 0.1% | +2% |
| Capital World Investors | 21.2M | 0.2% | +18% |
| BlackRock, Inc. | 10.4M | 0.0% | −2% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 7.8M | n/a | n/a |
| VANGUARD CAPITAL MANAGEMENT LLC | 7.1M | n/a | n/a |
| WELLINGTON MANAGEMENT GROUP LLP | 6.4M | 0.1% | +2% |
◇ AC INTELLIGENCE
Top institutional owners for IONS as of the most recent 13F reporting period (Q1 2026 · Period ended Mar 31). Δ Q/Q reflects share-count change vs. the prior filing — positive green means adding, negative red means trimming. Cross-reference with the ownership-mix bars below to see which strategy cohort is driving the flow.
§ 06 · WHO OWNS IT · BY STRATEGY
OTHER49.9% · 370 holders
QUALITY / COMPOUNDER34.6% · 34 holders
DEALER / BANK11.4% · 42 holders
PASSIVE / INDEX11.0% · 11 holders
SYSTEMATIC / QUANT1.8% · 11 holders
TACTICAL / MACRO1.6% · 4 holders
INCOME / DEFENSIVE1.4% · 22 holders
ACTIVIST0.3% · 1 holder
GROWTH / MOMENTUM0.0% · 1 holder
◇ AC INTELLIGENCE
Ownership mix by behavioral cohort. Top bars indicate which style of capital dominates the float — passive indexing, quality compounders, dealer/bank, systematic quant, etc. Big quality-compounder share means concentrated active conviction; heavy passive share means flows are dictated by index rebalances, not fundamentals.
§ 07 · INSIDER ACTIVITY · LAST 180 DAYS
NO INSIDER FILINGS
◇ AC INTELLIGENCE
No Form 4 filings on record for IONS in the last 180 days.