§ EQUITY
USDSPRO
SPERO THERAPEUTICS INC
USD
§ 01 · PRICE
Price action
1D5D1M6MYTD1YMAX
§ 03 · SIGNAL STACK · WHAT THE INPUTS SAY
13F FLOW
44 increased/new, 8 decreased/exited (13F)
AC 13F Analysis
§ 05 · WHO OWNS IT
Top institutional holders
| Fund | Shares | % port | Δ Q/Q |
|---|---|---|---|
| GSK plc | 9.2M | 3.6% | ±0% |
| Pfizer Inc | 2.4M | 2.3% | ±0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.8M | n/a | n/a |
| Renaissance Technologies | 1.2M | 0.0% | −7% |
| Alphabet Inc. | 890K | 0.1% | ±0% |
| TWO SIGMA INVESTMENTS, LP | 886K | 0.0% | +138% |
◇ AC INTELLIGENCE
Top institutional owners for SPRO as of the most recent 13F reporting period (Q1 2026 · Period ended Mar 31). Δ Q/Q reflects share-count change vs. the prior filing — positive green means adding, negative red means trimming. Cross-reference with the ownership-mix bars below to see which strategy cohort is driving the flow.
§ 06 · WHO OWNS IT · BY STRATEGY
OTHER85.1% · 30 holders
SYSTEMATIC / QUANT6.9% · 6 holders
PASSIVE / INDEX4.4% · 4 holders
TACTICAL / MACRO1.8% · 1 holder
DEALER / BANK1.6% · 9 holders
QUALITY / COMPOUNDER0.1% · 1 holder
◇ AC INTELLIGENCE
Ownership mix by behavioral cohort. Top bars indicate which style of capital dominates the float — passive indexing, quality compounders, dealer/bank, systematic quant, etc. Big quality-compounder share means concentrated active conviction; heavy passive share means flows are dictated by index rebalances, not fundamentals.
§ 07 · INSIDER ACTIVITY · LAST 180 DAYS
NO INSIDER FILINGS
◇ AC INTELLIGENCE
No Form 4 filings on record for SPRO in the last 180 days.