§ BIOTECHNOLOGY
USD · BiotechnologyUPB
UPSTREAM BIO INC
USDSector · Biotechnology
§ 01 · PRICE
Price action
1D5D1M6MYTD1YMAX
§ 03 · SIGNAL STACK · WHAT THE INPUTS SAY
§ 05 · WHO OWNS IT
Top institutional holders
| Fund | Shares | % port | Δ Q/Q |
|---|---|---|---|
| Fidelity Management | 7.2M | 0.0% | +8% |
| ORBIMED ADVISORS LLC | 5.7M | 1.0% | ±0% |
| Decheng Capital LLC | 2.7M | 3.7% | −13% |
| ENAVATE SCIENCES GP, LLC | 2.5M | 6.3% | ±0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.9M | 0.0% | n/a |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.9M | 0.0% | n/a |
◇ AC INTELLIGENCE
Top institutional owners for UPB as of the most recent 13F reporting period (Q1 2026 · Period ended Mar 31). Δ Q/Q reflects share-count change vs. the prior filing — positive green means adding, negative red means trimming. Cross-reference with the ownership-mix bars below to see which strategy cohort is driving the flow.
§ 06 · WHO OWNS IT · BY STRATEGY
OTHER11.5% · 0 holders
OTHER49.8% · 94 holders
QUALITY / COMPOUNDER18.8% · 12 holders
PASSIVE / INDEX8.7% · 7 holders
DEALER / BANK6.8% · 16 holders
TACTICAL / MACRO1.9% · 3 holders
ACTIVIST1.5% · 1 holder
SYSTEMATIC / QUANT0.8% · 7 holders
INCOME / DEFENSIVE0.2% · 5 holders
◇ AC INTELLIGENCE
Ownership mix by behavioral cohort. Top bars indicate which style of capital dominates the float — passive indexing, quality compounders, dealer/bank, systematic quant, etc. Big quality-compounder share means concentrated active conviction; heavy passive share means flows are dictated by index rebalances, not fundamentals.
§ 07 · INSIDER ACTIVITY · LAST 180 DAYS
NO INSIDER FILINGS
◇ AC INTELLIGENCE
No Form 4 filings on record for UPB in the last 180 days.
§ 08 · COVERAGE · OUR RECENT NOTES
No notes mention UPB yet.